Development of environmentally acceptable replacements for DDT

UI CONTINUES RESEARCH AND TESTING OF AT LEAST EIGHT DDT ANALOGUES THROUGH WHO PHASE-1 LABORATORY TRIALS. POTENTIAL DDT SUBSTITUTES TESTED FOR HIGH INSECTICIDAL ACTIVITY AGAINST DISEASE VECTORS AND AGRICULTURAL PESTS, BIODEGRADABILITY, REDUCED TOXICITY TO FISH, EFFECTIVENESS AGAINST DDT-RESISTANT INSECT SPECIES, TOXICITY TO HIGHER ORDER ANIMALS. COOPERATING ORGANIZATIONS IN TEST SEQUENCE INCLUDE UI, ILLINOIS STATE NATURAL HISTORY SOCIETY, USPHS/CSC, LONDON SCHOOL OF TROPICAL MEDICINE AND HYGIENE, USDA AND WHO. ORGANIZATIONS PROVIDE BASIC RESEARCH AND TEST LABORATORIES, INSECTARY FACILITIES, TEST PLOTS AND A WIDE SPECTRUM OF INSECT TEST SPECIES. WHO PARTICIPATION INCLUDES ESTABLISHMENT AND OPERATION OF INSECTICIDE TESTING FACILITIES AT SEMARANG, INDONESIA, BASELINE SURVEYS, INSECTICIDE FIELD TESTS, POST-TEST EPIDEMIOLOGICAL EVALUATION FOR INSECTICIDES" EFFICACY. WHO CERTIFICATION OF OMS-43 THROUGH PHASE-7 AND ONE OR MORE UI DDT ANALOGUE COMPOUNDS THROUGH PHASE-5 ANTICIPATED BY END OF PROJECT FOR USE IN PUBLIC HEALTH MALARIA CONTROL AND/OR AGRICULTURAL PEST CONTROL PROGRAMS IN DEVELOPING COUNTRIES. PROJECT DURATION JULY 1972-JULY 1975. Amendment dated 6/27/81 provides additional funding to extend project for one year from FY 81 through FY 82. Amendment will provide the WHO sufficient lead time to secure additional funding from other sources to extend the project past FY 82. During the next year, one or more state-of-the-art workshops will be sponsored by A.I.D. to develop policy and program guidance for the Comprehensive Vector Control Program (931-1179).