USAID DEC
Human Immunodeficiency Virus (HIV) is a viral infection that attacks the body's immune system.
62 pages

Abstract
The virus is transmitted through bodily fluids, including blood, semen, and breast milk. HIV targets the CD4 cells, also known as T cells, which play a crucial role in the immune system's ability to fight off infections. The virus works by infecting and destroying CD4 cells, leading to a weakened immune system. This makes the individual more susceptible to opportunistic infections and certain types of cancer. If left untreated, HIV can progress to Acquired Immune Deficiency Syndrome (AIDS), a condition characterized by severe damage to the immune system. HIV is a global health concern, with millions of people infected worldwide. The virus is most commonly spread through unprotected sex, sharing needles, and from mother to child during pregnancy, childbirth, or breastfeeding. There is no cure for HIV, but antiretroviral therapy (ART) can effectively manage the infection and prevent the progression to AIDS. ART involves a combination of medications that work together to suppress the virus. The treatment regimen typically includes a combination of three or more medications, which are taken daily to maintain viral suppression. Adherence to the treatment plan is crucial to prevent the development of drug-resistant strains of the virus. In addition to ART, other interventions are being explored to prevent the spread of HIV. These include pre-exposure prophylaxis (PrEP), a medication taken by individuals at high risk of infection to prevent HIV acquisition. Post-exposure prophylaxis (PEP) is also available, which involves taking antiretroviral medications within 72 hours of potential exposure to HIV. Research is ongoing to develop a vaccine against HIV, but so far, none have been proven to be effective in preventing the infection. However, several promising candidates are in various stages of development, and it is hoped that a vaccine will become available in the near future. The World Health Organization (WHO) and other global health authorities have implemented various strategies to combat the HIV epidemic. These include increasing access to ART, promoting safe sex practices, and providing education and awareness about HIV prevention and treatment.
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USAID DEC