Why do we need the pentavalent vaccine ? EPI Program, Timor-Leste

The Pentavalent Vaccine combines five antigens (DPT, HepB, and Hib) in a single formulation. The Pentavalent Vaccine is available in the EPI in a presentation of 10 doses. The vaccine requires storage at a temperature range of 2-80C, in an ice-lined refrigerator, and must be labeled with the date. During transportation, the vaccine must be kept in an ice pack that has been conditioned to prevent the vaccine from spoiling. The vaccine administrator must perform a shake test on the vaccine that has been compromised, and the vaccine that passes the test must be returned to the National Immunization Program (SAMES). The recommended routine schedule for the Pentavalent Vaccine involves three doses. The first dose is administered to children at six weeks of age or older. The second dose is administered at six weeks, followed by a third dose at 14 weeks. The interval between doses (Hib) is one month. The Pentavalent Vaccine has a dose of 0.5 ml, administered in the same manner as the DPT vaccine. The vaccine is used directly from the vial and administered intramuscularly in the child's left upper arm. The Hib component of the vaccine is not associated with serious adverse effects, but mild reactions such as redness, swelling, and pain at the injection site may occur in up to 25% of recipients. The Pentavalent Vaccine is safe and effective, providing protection of 85-95% when completed in the recommended schedule. The vaccine is similar to the DPT-HepB vaccine in terms of its management and storage. The introduction of the Pentavalent Vaccine requires commitment and support from various departments and ministries, including the police, Ministry of Social Solidarity, schools, and non-governmental organizations, churches, community groups, and leaders. The Pentavalent Vaccine has excellent record-keeping, is 95% effective against invasive Hib disease, and is integrated into the EPI schedule. The vaccine interrupts transmission and protects the community through herd immunity. The routine schedule for the Pentavalent Vaccine is designed to eliminate Hib disease. The vaccine is a pentavalent formulation, which is an improvement over the existing tetravalent vaccine, and does not require additional space or capacity. The introduction of the Pentavalent Vaccine does not require additional injections or visits for children. The administration of the vaccine is similar to the tetravalent vaccine, and does not require special training. Health workers must allocate time to inform village chiefs, community leaders, and other authorities about the new vaccine and its benefits for children and the community. It is recommended to refer to the guide for health workers for questions and possible responses from mothers and their families.